Region VI is located in the southwest corner of Pennsylvania and features the towns of Bloomfield, Centre, East Liverpool, East Mifford, Grays, Huntingdon, Lebanon, North Versailles, Oxford, Raynham, and Warren. It is a small community that prides itself on the care it provides to its residents. The town of Bloomfield is where the first substance abuse treatment center in the state of Pennsylvania was built. This community features a hospital and two outpatient treatment centers. The center features all the latest technology and skilled professionals who treat patients with compassion and without judgment.

The other inpatient substance abuse treatment center is located in Huntingdon. It is a four hundred fifty-bed facility that is dedicated to treating all forms of mental illnesses including drug addiction. The hospital is a division of the University of Maryland Medical System. This center offers inpatient substance abuse treatment and psychiatric nursing care.

The last inpatient community mental health services center in this area is located in Centre, formerly known as Bloomfield. This location is part of the new town of Centreville. This community features the only all-inclusive lifestyle community in Southwest Pennsylvania. With a strong foundation of community based, integrated, and faith-based service programs, the residents are provided with the best care available.